Rheumatoid Arthritis is a chronic inflammatory disease . It‘s a systemic and autoimmune disease . It‘s the most frequent inflammatory disease .Its frequency is different according to the land . In France its prevalence is 230 for 100 000 inhabitants .
Generally, It occurs at the age of fifty years . But in Morocco we noticed that the Onset of the disease is earlier at the age of thirty. (article of Pr BENAMOUR at revue of rheumatism : Rheumatoid Arthritis in Morocco ) .
This disease involves several joints : mainly hands, feet and cervical spine but can propagate to others articulations . It’s often bilateral and symmetrical , involving hands and others articulations. Joint pains are worsening at the second phase of the night with a morning stiffness .At awake, joints are swelling , stiffed and warm so that we call it arthritis . This symptoms are developing by access more and more important and can lead to joint destruction and deformations with huge handicap . Extra-Articular manifestations can be observed: such as subcutaneous nodules , pulmonary, cardiac and neurological involvements . The assessment of the diagnosis is based on clinical, X Rays and biology : Rheumatoid factor and anti CCP antibodies .